Delirium secondary to intrathecal baclofen
Por:
Castano, B, Benito, J, Pires, F, Ferreira, S, Lopez, R and Vidal, J
Publicada:
1 jun 2009
Resumen:
Study design: Retrospective study based on a revision of the clinical histories of all patients carrying an intrathecal baclofen (ITB) infusion system between July 1988 and March 2007 in a neurorehabilitation hospital.
Objectives: To describe the psychiatric manifestations due to intoxication or withdrawal of ITB and to explore the possible risk factors for the presentation of delirium secondary to baclofen.
Setting: Spinal Cord Injury Unit in Barcelona, Spain.
Methods: We selected patients who presented delirium related to baclofen treatment. We filtered these cases by the search of key words. All the compatible episodes were then reviewed and positive cases were confirmed to perform a descriptive analysis of the different variables. Control subjects were randomly selected for a comparative analysis of the aspects of interest.
Results: A total of 12 of the 126 patients carrying the intrathecal system in our hospital presented delirium related to baclofen. Eight cases due to intoxication (66.6%) and four due to withdrawal (33.3%) were found. We provide a description of the psychiatric symptoms. There were no fatal cases due to delirium.
Conclusion: Delirium has a frequency of 9.5% in patients carrying the ITB infusion system, intoxication being more frequent than withdrawal. Spinal Cord (2009) 47, 477-480; doi:10.1038/sc.2008.156; published online 16 December 2008
Filiaciones:
Castano, B:
Neurorehabil Hosp, Inst Guttmann, Spinal Cord Injury Unit, Badalona 08916, Spain
:
Neurorehabil Hosp, Inst Guttmann, Spinal Cord Injury Unit, Badalona 08916, Spain
Pires, F:
Hosp Sao Joao, Oporto, Portugal
Ferreira, S:
Hosp Senhora da Oliveira, Guimaraes, Portugal
Lopez, R:
Neurorehabil Hosp, Inst Guttmann, Spinal Cord Injury Unit, Badalona 08916, Spain
:
Neurorehabil Hosp, Inst Guttmann, Spinal Cord Injury Unit, Badalona 08916, Spain
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