Concomitant genomic alterations in KRAS mutant advanced lung adenocarcinoma.


Por: Gibert J, Clavé S, Hardy-Werbin M, Taus Á, Rocha P, Longarón R, Piquer G, Chaib I, Carcereny E, Morán T, Salido M, Dalmases A, Bellosillo B and Arriola E

Publicada: 1 feb 2020 Ahead of Print: 5 dic 2019
Resumen:
KRAS mutations are one of the most prevalent alterations in non-small cell lung cancer. However, patients with this driver alteration present heterogeneous clinical outcomes. In this study, we have explored the potential clinical impact of coexisting alterations in this subset of patients.

Filiaciones:
Gibert J:
 Cancer Research Program, Hospital del Mar Medical Research Institute, Barcelona, Spain

Clavé S:
 Cancer Research Program, Hospital del Mar Medical Research Institute, Barcelona, Spain

 Pathology Department, Hospital del Mar, Barcelona, Spain

Hardy-Werbin M:
 Cancer Research Program, Hospital del Mar Medical Research Institute, Barcelona, Spain

Taus Á:
 Medical Oncology Department, Hospital del Mar - CIBERONC, Barcelona, Spain

Rocha P:
 Medical Oncology Department, Hospital del Mar - CIBERONC, Barcelona, Spain

Longarón R:
 Cancer Research Program, Hospital del Mar Medical Research Institute, Barcelona, Spain

 Pathology Department, Hospital del Mar, Barcelona, Spain

Piquer G:
 Cancer Research Program, Hospital del Mar Medical Research Institute, Barcelona, Spain

 Pathology Department, Hospital del Mar, Barcelona, Spain

:
 Medical Oncology Department, Catalan Institute of Oncology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain

:
 Medical Oncology Department, Catalan Institute of Oncology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain

:
 Medical Oncology Department, Catalan Institute of Oncology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain

Salido M:
 Cancer Research Program, Hospital del Mar Medical Research Institute, Barcelona, Spain

 Pathology Department, Hospital del Mar, Barcelona, Spain

Dalmases A:
 Cancer Research Program, Hospital del Mar Medical Research Institute, Barcelona, Spain

 Pathology Department, Hospital del Mar, Barcelona, Spain

Bellosillo B:
 Cancer Research Program, Hospital del Mar Medical Research Institute, Barcelona, Spain

 Pathology Department, Hospital del Mar, Barcelona, Spain

Arriola E:
 Cancer Research Program, Hospital del Mar Medical Research Institute, Barcelona, Spain

 Medical Oncology Department, Hospital del Mar - CIBERONC, Barcelona, Spain
ISSN: 01695002





Lung Cancer
Editorial
Elsevier BV, ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND, Países Bajos
Tipo de documento: Article
Volumen: 140 Número:
Páginas: 42-45
WOS Id: 000510532900006
ID de PubMed: 31862576

MÉTRICAS