Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018
Por:
Spitaleri, G, Lupon, J, Domingo, M, Santiago-Vacas, E, Codina, P, Zamora, E, Cediel, G, Santesmases, J, Diez-Quevedo, C, Troya, MI, Boldo, M, Altmir, S, Alonso, N, Gonzalez, B, Nunez, J and Bayes-Genis, A
Publicada:
12 ene 2021
Ahead of Print:
12 ene 2021
Resumen:
To assess mortality trends at 1 and 3 years from 2001 to 2018 in a real-life cohort of HF outpatients from different etiologies with depressed and preserved LVEF. A total of 2368 consecutive patients with HF (mean age 66.4 +/- 12.9 years, 71% men, 15.4% with preserved LVEF) admitted to a HF clinic from August 2001 to September 2018 were included in the study. Patients were divided into five quintiles (Q) according to the period of admission. Trends for all-cause and cardiovascular mortality from Q1 to Q5 were assessed by linear regression. Patients with LVEF<50% had a progressive decrease in the rates of all-cause and cardiovascular death at 1 year (12.1% in Q1 to 6.5% in Q5, p=0.003; and 8.4% in Q1 to 3.8% in Q5, p=0.007, respectively) and 3 years (30.5% in Q1 to 17.0% in Q5, p=0.003; and 23.9% in Q1 to 9.8% in Q5, p=0.003, respectively). These trends remained significant after adjusting for clinical characteristics and risk. No significant trend in mortality was observed in patients with LVEF >= 50%. In a cohort of real-life ambulatory patients with HF, mortality progressively declined in patients with LVEF<50%, but the same trend was not observed in patients with preserved LVEF.
Filiaciones:
Spitaleri, G:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
Univ Autonoma Barcelona, Dept Med, Barcelona, Spain
Inst Salud Carlos III, CIBERCV, Madrid, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
Univ Autonoma Barcelona, Dept Med, Barcelona, Spain
Inst Salud Carlos III, CIBERCV, Madrid, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
Univ Autonoma Barcelona, Dept Med, Barcelona, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
Univ Autonoma Barcelona, Dept Med, Barcelona, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
Altmir, S:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
Nunez, J:
Inst Salud Carlos III, CIBERCV, Madrid, Spain
Hosp Clin Univ, Cardiol Dept, INCLIVA, Valencia, Spain
Univ Valencia, Dept Med, Valencia, Spain
:
Univ Hosp Germans Trias & Pujol, Heart Failure Clin & Cardiol Serv, Badalona, Spain
Univ Autonoma Barcelona, Dept Med, Barcelona, Spain
Inst Salud Carlos III, CIBERCV, Madrid, Spain
Univ Autonoma Barcelona, Hosp Univ Germans Trias & Pujol, Heart Inst, Dept Med, Carretera Canyet S-N, Badalona 08916, Spain
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