Thirst distress in outpatients with heart failure in a Mediterranean zone of Spain


Por: Eng, SH, Waldreus, N, Gonzalez, B, Ehrlin, J, Diaz, V, Rivas, C, Velayos, P, Puertas, M, Ros, A, Martin, P, Lupon, J, Bayes-Genis, A and Jaarsma, T

Publicada: 1 ago 2021 Ahead of Print: 1 may 2021
Resumen:
Aims This study aimed to evaluate psychometric properties of the Spanish version of the Thirst Distress Scale for patients with Heart Failure (TDS-HF) and to describe thirst distress-associated factors in outpatients at a heart failure (HF) clinic in Spain. Thirst is common in patients with HF, but thirst distress has rarely been addressed and may significantly decrease quality of life. Methods and results A cross-sectional study was performed assessing perceived thirst distress by patients with HF during the preceding 3 days, with the TDS-HF (scores 8 to 40). Univariable and multivariable linear regression analyses were performed to identify variables independently associated with thirst distress. Three-hundred two HF outpatients were included (age 67 +/- 12 years, 74% male, HF duration 82 +/- 75 months, left ventricular ejection fraction 42 +/- 14%). Most patients were on treatment with fluid restriction (99%), sodium restriction (99%), and diuretics (70%). The psychometric evaluation of the Spanish version of the TDS-HF showed satisfactory item-total and inter-item correlations (range from 0.77 to 0.85 and 0.60 to 0.84, respectively), and internal consistency was 0.95 (Cronbach's alpha). The majority perceived mild to moderate thirst distress, and 18% perceived it as high or severe. The mean score obtained was 16.2 +/- 9.3 (median 13, Q1-Q3 8-20). Higher serum urea {beta coefficient 1.6 [95% confidence interval (CI) 0.267 to 2.92], P = 0.019} and lower potassium [beta coefficient -3.63 (85% CI -6.32 to -0.93), P = 0.009] remained significantly associated with thirst distress in the multivariable analysis, together with the dose of diuretics [beta coefficient 2.98 (95% CI 1.37 to 4.59), P < 0.001]. Treatment with angiotensin receptor blocker showed an independent protective effect [beta coefficient -3.62 (95% CI -6.89 to -0.345), P = 0.03]. Conclusions The psychometric evaluation of the Spanish version of the TDS-HF showed good psychometric properties. One in five patients experienced severe distress by thirst, but the majority had mild to moderate thirst distress. The dose of diuretics and angiotensin receptor blocker treatment influence thirst distress and could be clinically important targets to relieve thirst distress in patients with HF.

Filiaciones:
Eng, SH:
 Linkoping Univ, Fac Med & Hlth Sci, SE-58183 Linkoping, Sweden

Waldreus, N:
 Karolinska Inst, Dept Neurobiol Care Sci & Soc, Huddinge, Sweden

 Karolinska Univ Hosp, Theme Aging, Stockholm, Sweden

:
 Hosp Badalona Germans Trias & Pujol, Heart Failure Unit, Badalona, Spain

Ehrlin, J:
 Linkoping Univ, Fac Med & Hlth Sci, SE-58183 Linkoping, Sweden

:
 Hosp Badalona Germans Trias & Pujol, Heart Failure Unit, Badalona, Spain

Rivas, C:
 Hosp Badalona Germans Trias & Pujol, Heart Failure Unit, Badalona, Spain

Velayos, P:
 Hosp Badalona Germans Trias & Pujol, Heart Failure Unit, Badalona, Spain

:
 Hosp Badalona Germans Trias & Pujol, Heart Failure Unit, Badalona, Spain

:
 Hosp Badalona Germans Trias & Pujol, Heart Failure Unit, Badalona, Spain

Martin, P:
 Hosp Badalona Germans Trias & Pujol, Heart Failure Unit, Badalona, Spain

:
 Hosp Badalona Germans Trias & Pujol, Heart Failure Unit, Badalona, Spain

 Univ Autonoma Barcelona, Dept Med, Barcelona, Spain

 Inst Salud Carlos III, CIBER Cardiovasc, Madrid, Spain

:
 Hosp Badalona Germans Trias & Pujol, Heart Failure Unit, Badalona, Spain

 Univ Autonoma Barcelona, Dept Med, Barcelona, Spain

 Inst Salud Carlos III, CIBER Cardiovasc, Madrid, Spain

Jaarsma, T:
 Linkoping Univ, Fac Med & Hlth Sci, SE-58183 Linkoping, Sweden
ISSN: 20555822





ESC Heart Failure
Editorial
The Heart Failure Association of the European Society of Cardiology, ONE MONTGOMERY ST, SUITE 1200, SAN FRANCISCO, CA 94104 USA, Reino Unido
Tipo de documento: Article
Volumen: 8 Número: 4
Páginas: 2492-2501
WOS Id: 000646402300001
ID de PubMed: 33942551
imagen gold, Green Published

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