In-hospital outcomes of COVID-19 ST-elevation myocardial infarction patients
Por:
Rodriguez-Leor, O, Cid-Alvarez, B, de Prado, AP, Rossello, X, Ojeda, S, Serrador, A, Lopez-Palop, R, Martin-Moreiras, J, Rumoroso, JR, Cequier, A, Ibanez, B, Cruz-Gonzalez, I, Romaguera, R and Moreno, R
Publicada:
1 abr 2021
Resumen:
Aims: The aim of this study was to assess clinical and prognosis differences in patients with COVID-19 and STEMI.
Methods and results: Using a nationwide registry of consecutive patients managed within 42 specific STEMI care networks, we compared patient and procedure characteristics and in-hospital outcomes in two different cohorts, according to whether or not they had COVID-19. Among 1,010 consecutive STEMI patients, 91 were identified as having COVID-19 (9.0%). With the exception of smoking status (more frequent in non-COVID-19 patients) and previous coronary artery disease (more frequent in COVID-19 patients), clinical characteristics were similar between the groups, but COVID-19 patients had more heart failure on arrival (31.9% vs 18.4%, p=0.002). Mechanical thrombectomy (44% vs 33.5%, p=0.046) and GP IIb/IIIa inhibitor administration (20.9% vs 11.2%, p=0.007) were more frequent in COVID-19 patients, who had an increased in-hospital mortality (23.1% vs 5.7%, p<0.0001), that remained consistent after adjustment for age, sex, Killip class and ischaemic time (OR 4.85, 95% CI: 2.04-11.51; p<0.001). COVID-19 patients had an increase of stent thrombosis (3.3% vs 0.8%, p=0.020) and cardiogenic shock development after PCI (9.9% vs 3.8%, p=0.007).
Conclusions: Our study revealed a significant increase in in-hospital mortality, stent thrombosis and cardiogenic shock development after PCI in patients with STEMI and COVID-19 in comparison with contemporaneous non-COVID-19 STEMI patients.
Methods and results: Using a nationwide registry of consecutive patients managed within 42 specific STEMI care networks, we compared patient and procedure characteristics and in-hospital outcomes in two different cohorts, according to whether or not they had COVID-19. Among 1,010 consecutive STEMI patients, 91 were identified as having COVID-19 (9.0%). With the exception of smoking status (more frequent in non-COVID-19 patients) and previous coronary artery disease (more frequent in COVID-19 patients), clinical characteristics were similar between the groups, but COVID-19 patients had more heart failure on arrival (31.9% vs 18.4%, p=0.002). Mechanical thrombectomy (44% vs 33.5%, p=0.046)
Filiaciones:
:
Hosp Badalona Germans Trias & Pujol, Inst Cor, Carretera Canyet SN, Badalona 08916, Spain
Inst Salud Carlos III, CIBER Enfermedades Cardiovasc CIBERCV, Madrid, Spain
Inst Rec Ciencies Salut Germans Trias & Pujol, Badalona, Spain
Cid-Alvarez, B:
Hosp Clin Santiago Compostela, Cardiol Dept, Santiago De Compostela, Spain
de Prado, AP:
Hosp Leon, Cardiol Dept, Leon, Spain
Rossello, X:
Ctr Nacl Invest Cardiovasc Carl III CNIC, Madrid, Spain
Hosp Univ Son Espases, Hlth Res Inst Balear Isl IdISBa, Cardiol Dept, Palma De Mallorca, Spain
Ojeda, S:
Univ Cordoba, Hosp Univ Reina Sofia, IMIBIC, Cardiol Dept, Cordoba, Spain
Serrador, A:
Inst Salud Carlos III, CIBER Enfermedades Cardiovasc CIBERCV, Madrid, Spain
Hosp Clin Valladolid, Cardiol Dept, Valladolid, Spain
Lopez-Palop, R:
Hosp Virgen Arrixaca, Cardiol Dept, Murcia, Spain
Martin-Moreiras, J:
Inst Salud Carlos III, CIBER Enfermedades Cardiovasc CIBERCV, Madrid, Spain
Hosp Univ Salamanca, IBSAL, Cardiol Dept, Salamanca, Spain
Rumoroso, JR:
Hosp GaldakaoUsansolo, Cardiol Dept, Galdakao, Vizcaya, Spain
Cequier, A:
Univ Barcelona, Hosp Bellvitge IDIBELL, Cardiol Dept, Barcelona, Spain
Ibanez, B:
Inst Salud Carlos III, CIBER Enfermedades Cardiovasc CIBERCV, Madrid, Spain
Cruz-Gonzalez, I:
Inst Salud Carlos III, CIBER Enfermedades Cardiovasc CIBERCV, Madrid, Spain
Romaguera, R:
Univ Barcelona, Hosp Bellvitge IDIBELL, Cardiol Dept, Barcelona, Spain
Moreno, R:
Inst Salud Carlos III, CIBER Enfermedades Cardiovasc CIBERCV, Madrid, Spain
Hosp La Paz, Cardiol Dept, Madrid, Spain
IIS Fdn Jimenez Diaz Univ Hosp, Cardiol Dept, Madrid, Spain.
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