Study protocol for monitoring SARS-CoV-2 infection and its determinants in Catalonia (Spain): an observational and participatory research approach in a Sentinel Network of Schools
Por:
Bordas, A, Soriano-Arandes, A, Subirana, M, Malagrida, R, Reyes-Uruena, JM, Folch, C, Soler-Palacin, P, Gascon, M, Sunyer, J, Anton, A, Blanco, I, Fernandez-Morales, J, Colom-Cadena, A, Sentis, A, Pumarola, T, Basora, J and Casabona, J
Publicada:
1 ene 2022
Resumen:
Introduction Since the SARS-CoV-2 became of concern in January 2020, many preventive measures have been adopted in educational settings to ensure the control of COVID-19 pandemic among children and staff in schools. This study aims to set up a school sentinel surveillance network with the purpose of monitoring SARS-CoV-2 infection, seroprevalence as well as to analyse the impact of preventive interventions of SARS-CoV-2 in school settings. Additionally, we will assess diverse screening strategies in a cohort of students and school staff to monitor the screening acceptance and its potential impact. Altogether, we hope this study will enable the design of more effective strategies for the prevention of COVID-19 spread. Methods and analysis The sentinel schools' study is a cross-sectional, school-based project including 26 participating sentinel schools in Catalonia (Spain). Children, adolescents and staff at the schools will be invited to participate. This project will be carried out from January 2021 to June 2022 as follows: (1) twice yearly serological testing and molecular SARS-CoV-2 detection and questionnaires covering SARS-CoV-2 symptoms, tests, health, knowledge, attitudes and behaviours; (2) an environmental evaluation carried out in different classrooms; (3) SARS-CoV-2 transmission dynamics and the impact of different variants among confirmed cases and classmates; (4) a participatory process by which the participants are invited to act as coinvestigators to evaluate prevention strategies and provide recommendations to improve COVID-19 prevention in schools. Descriptive analysis will be performed for the main variables collected. The incidence and seroprevalence will be calculated and the association with sociodemographic factors and school characteristics will be determined using multivariate logistic regression. Ethics and dissemination Ethical approval was obtained from the IDIAPJGol and the Hospital Universitari Vall d'Hebron ethics committees. A report will be generated quarterly. Findings will be disseminated at national and international conferences and published in peer-reviewed journals.
Filiaciones:
:
Generalitat Catalunya, Hlth Dept, Ctr Epidemiol Studies HIV SIDA & STI Catalonia CE, Badalona, Catalunya, Spain
Inst Hlth Sci Res Germans Trias & Pujol IGTP, Badalona, Spain
Soriano-Arandes, A:
Univ Autonoma Barcelona, Hosp Vall dHebron, Vall dHebron Inst Recerca, Pediat Infect Dis & Immunodeficiencies Unit, Barcelona, Catalunya, Spain
Subirana, M:
IMIM Parc Salut Mar, Barcelona Inst Global Hlth, Barcelona, Catalunya, Spain
Univ Pompeu Fabra, Barcelona, Catalunya, Spain
:
IrsiCaixa Aids Res Inst, Living Lab Hlth, Badalona, Catalunya, Spain
:
Generalitat Catalunya, Hlth Dept, Ctr Epidemiol Studies HIV SIDA & STI Catalonia CE, Badalona, Catalunya, Spain
Inst Salud Carlos III, Spanish Consortium Res Epidemiol & Publ Hlth CIBE, Madrid, Comunidad Madri, Spain
:
Generalitat Catalunya, Hlth Dept, Ctr Epidemiol Studies HIV SIDA & STI Catalonia CE, Badalona, Catalunya, Spain
Inst Hlth Sci Res Germans Trias & Pujol IGTP, Badalona, Spain
Inst Salud Carlos III, Spanish Consortium Res Epidemiol & Publ Hlth CIBE, Madrid, Comunidad Madri, Spain
Soler-Palacin, P:
Univ Autonoma Barcelona, Hosp Vall dHebron, Vall dHebron Inst Recerca, Pediat Infect Dis & Immunodeficiencies Unit, Barcelona, Catalunya, Spain
Gascon, M:
Univ Pompeu Fabra, Barcelona, Catalunya, Spain
ISGlobal, Ctr Int Hlth Res CRESIB, Barcelona, Catalunya, Spain
Sunyer, J:
Univ Pompeu Fabra, Barcelona, Catalunya, Spain
ISGlobal, IMIM Parc Salut Mar, Barcelona, Catalunya, Spain
Anton, A:
Univ Autonoma Barcelona, Hosp Univ Vall dHebron, Inst Catala Salut, Microbiol Dept, Barcelona, Catalunya, Spain
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Hosp Badalona Germans Trias & Pujol, Inst Invest Ciencies Salut Germans Trias & Pujol, Inst Catala Salut, Microbiol Dept,Lab Clin Metropolitana Nord, Barcelona, Catalunya, Spain
Fernandez-Morales, J:
IrsiCaixa Aids Res Inst, Living Lab Hlth, Badalona, Catalunya, Spain
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Generalitat Catalunya, Hlth Dept, Ctr Epidemiol Studies HIV SIDA & STI Catalonia CE, Badalona, Catalunya, Spain
Inst Hlth Sci Res Germans Trias & Pujol IGTP, Badalona, Spain
:
Generalitat Catalunya, Hlth Dept, Ctr Epidemiol Studies HIV SIDA & STI Catalonia CE, Badalona, Catalunya, Spain
Epiconcept SAS, Paris, Ile De France, France
Pumarola, T:
Univ Autonoma Barcelona, Hosp Univ Vall dHebron, Inst Catala Salut, Microbiol Dept, Barcelona, Catalunya, Spain
Basora, J:
Fdn Univ Inst Res Primary Hlth Care Jordi Gol & G, Barcelona, Catalunya, Spain
:
Generalitat Catalunya, Hlth Dept, Ctr Epidemiol Studies HIV SIDA & STI Catalonia CE, Badalona, Catalunya, Spain
Inst Hlth Sci Res Germans Trias & Pujol IGTP, Badalona, Spain
Inst Salud Carlos III, Spanish Consortium Res Epidemiol & Publ Hlth CIBE, Madrid, Comunidad Madri, Spain
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