Effects of Mixing Energy Drinks With Alcohol on Driving-Related Skills
Por:
Perez-Mana, C, Mateus, JA, Diaz-Pellicer, P, Diaz-Baggerman, A, Perez, M, Pujadas, M, Fonseca, F, Papaseit, E, Pujol, J, Langohr, K and de la Torre, R
Publicada:
1 ene 2022
Ahead of Print:
1 ago 2021
Resumen:
Background: Energy drinks (EDs) reduce sleepiness and fatigue and improve driving performance whereas alcohol does just the opposite. Although it is a trendy combination among young people, the effects of alcohol mixed with EDs on driving performance have been poorly studied. The aim was to assess if there is an interaction between the effects of both drinks on driving-related skills as well as perceptions about driving ability.
Methods: We conducted a randomized, double-blind, and placebo-controlled 4-way crossover clinical trial. Participants were 16 healthy volunteers. Interventions of 60 g of ethanol and 750 mL of Red Bull (RB) were administered in 2 separated doses. Conditions were alcohol + RB placebo, alcohol + RB, alcohol placebo + RB, and both placebos. Objective performance was assessed using a tracking test and simple reaction time, N-Back, and movement estimation tasks. Additionally, willingness to drive, other subjective effects, and ethanol and caffeine blood concentrations were also measured.
Results: Alcohol increased the time outside the road in the tracking test and increased simple reaction time, but the addition of RB had no main or interaction effects on performance. Nonetheless, driving-related skills after alcohol + RB were better than after alcohol alone. Willingness to drive increased with the combination of drinks. RB also reduced alcohol-induced sedation whereas drunkenness did not change. These effects were seen even though alcohol + RB increased alcohol (14.8%) and caffeine plasma concentrations (17.6%).
Conclusions: Mixing EDs with alcohol predisposes consumers to drive under alcohol influence, perhaps in part because EDs counteract its detrimental effects on driving-related skills.
Filiaciones:
:
Hosp Univ Germans Trias I Pujol HUGTP IGTP, Clin Pharmacol Unit, Badalona, Spain
Hosp Mar Med Res Inst IMIM, Neurosci Res Program, Integrat Pharmacol & Syst Neurosci Res Grp, Barcelona, Spain
Autonomous Univ Barcelona UAB, Dept Pharmacol Therapeut & Toxicol, Cerdanyola Del Valles, Spain
Mateus, JA:
Hosp Mar Med Res Inst IMIM, Neurosci Res Program, Integrat Pharmacol & Syst Neurosci Res Grp, Barcelona, Spain
Autonomous Univ Barcelona UAB, Dept Pharmacol Therapeut & Toxicol, Cerdanyola Del Valles, Spain
Diaz-Pellicer, P:
Hosp Mar Med Res Inst IMIM, Neurosci Res Program, Integrat Pharmacol & Syst Neurosci Res Grp, Barcelona, Spain
Diaz-Baggerman, A:
Univ Barcelona UB, Neurosci Master, Barcelona, Spain
Perez, M:
Hosp Mar Med Res Inst IMIM, Neurosci Res Program, Integrat Pharmacol & Syst Neurosci Res Grp, Barcelona, Spain
Pujadas, M:
Hosp Mar Med Res Inst IMIM, Neurosci Res Program, Integrat Pharmacol & Syst Neurosci Res Grp, Barcelona, Spain
Fonseca, F:
Hosp Mar Med Res Inst IMIM, Inst Neuropsychiat & Addict INAD, Drug Addict Unit, Barcelona, Spain
:
Hosp Univ Germans Trias I Pujol HUGTP IGTP, Clin Pharmacol Unit, Badalona, Spain
Autonomous Univ Barcelona UAB, Dept Pharmacol Therapeut & Toxicol, Cerdanyola Del Valles, Spain
Pujol, J:
Hosp del Mar, MRI Res Unit, CIBERSAM G21, Barcelona, Spain
Langohr, K:
Polytech Univ Catalonia BarcelonaTech, Dept Stat & Operat Res, Barcelona, Spain
de la Torre, R:
Hosp Mar Med Res Inst IMIM, Neurosci Res Program, Integrat Pharmacol & Syst Neurosci Res Grp, Barcelona, Spain
Pompeu Fabra Univ CEXS UPF, Barcelona, Spain
Inst Salud Carlos III, CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
Green Published, gold
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