Noninvasive Brain Stimulation and Noninvasive Peripheral Stimulation for Neglect Syndrome Following Acquired Brain Injury
Por:
Lucente, G, Valls-Sole, J, Murillo, N, Rothwell, J, Coll, J, Davalos, A and Kumru, H
Publicada:
1 abr 2020
Ahead of Print:
1 nov 2019
Resumen:
Objective Hemispatial neglect is a frequent condition usually following nondominant hemispheric brain injury. It strongly affects rehabilitation strategies and everyday life activities. It is associated with behavioral and cognitive disability with a strong impact on patient's life. Methods We reviewed the published literature on the use of noninvasive brain stimulation, including repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), and of noninvasive peripheral muscle stimulation, as therapeutic strategies for rehabilitation of neglect after acquired brain injury, such as in stroke or in traumatic injuries. The studies were grouped as controlled or uncontrolled studies in each stimulation techniques. Results Thirty-four studies were identified and 16 on rTMS, 10 on tDCS, and 8 on vibration. All studies were conducted in adult patients who suffered a stroke, except for one that was conducted in a patient suffering traumatic acquired brain injury and another that was conducted in a patient with brain tumor. In spite of significant variability in treatment protocols, patients' features and assessment of neglect, improvement was reported in almost all studies with no side-effects. Conclusions Noninvasive brain stimulation and neuromuscular vibration are promising therapeutic neuromodulatory approaches for neglect. Further randomized-controlled studies are needed to corroborate their effectiveness as separate and combined techniques.
Filiaciones:
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Hosp Badalona Germans Trias & Pujol, Dept Neurosci, Badalona, Spain
Univ Autonoma Barcelona, Dept Neurosci, Grup Recerca Malalties Neuromusculars & Neuropedi, Inst Invest Ciencies Salut Germans Trias & Pujol, Badalona, Spain
Univ Autonoma Barcelona, Med Dept, Bellaterra 08193, Cerdanyola Del, Spain
Fundacio Inst Invest Ciencies Salut Germans Trial, Badalona, Spain
Valls-Sole, J:
Hosp Clin Barcelona, EMG Dept, Carrer Villarroel 170, Barcelona 08036, Spain
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Univ Autonoma Barcelona, Med Dept, Bellaterra 08193, Cerdanyola Del, Spain
Fundacio Inst Invest Ciencies Salut Germans Trial, Badalona, Spain
UAB, Fdn Inst Guttmann, Inst Univ Neurorehabil Adscrit, Badalona 08916, Spain
Rothwell, J:
UCL, Inst Neurol, Sobel Dept Motor Neurosci & Movement Disorders, Queen Sq, London, England
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Hosp Badalona Germans Trias & Pujol, Dept Neurosci, Badalona, Spain
Univ Autonoma Barcelona, Dept Neurosci, Grup Recerca Malalties Neuromusculars & Neuropedi, Inst Invest Ciencies Salut Germans Trias & Pujol, Badalona, Spain
Univ Autonoma Barcelona, Med Dept, Bellaterra 08193, Cerdanyola Del, Spain
Fundacio Inst Invest Ciencies Salut Germans Trial, Badalona, Spain
:
Hosp Badalona Germans Trias & Pujol, Dept Neurosci, Badalona, Spain
Univ Autonoma Barcelona, Med Dept, Bellaterra 08193, Cerdanyola Del, Spain
Fundacio Inst Invest Ciencies Salut Germans Trial, Badalona, Spain
:
Hosp Badalona Germans Trias & Pujol, Dept Neurosci, Badalona, Spain
UCL, Inst Neurol, Sobel Dept Motor Neurosci & Movement Disorders, Queen Sq, London, England
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