2019 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer


Por: Farge, D, Frere, C, Connors, JM, Ay, C, Khorana, AA, Muno, ZA, Brenner, B, Kakkar, A, Rafii, H, Solymoss, S, Brilhante, D, Monreal, M, Bounameaux, H, Pabinger, I and Douketis, J

Publicada: 1 oct 2019 Ahead of Print: 3 sep 2019
Categoría: Oncology

Resumen:
Venous thromboembolism (VTE) is the second leading cause of death in patients with cancer. These patients are at a high risk of VTE recurrence and bleeding during anticoagulant therapy. The International Initiative on Thrombosis and Cancer is an independent academic working group aimed at establishing a global consensus for the treatment and prophylaxis of VTE in patients with cancer. The International Initiative on Thrombosis and Cancer last updated its evidence-based clinical practice guidelines in 2016 with a free, web-based mobile phone application, which was subsequently endorsed by the International Society on Thrombosis and Haemostasis. The 2019 International Initiative on Thrombosis and Cancer clinical practice guidelines, which are based on a systematic review of the literature published up to December, 2018, are presented along with a Grading of Recommendations Assessment Development and Evaluation scale methods, with the support of the French National Cancer Institute. These guidelines were reviewed by an expanded international advisory committee and endorsed by the International Society on Thrombosis and Haemostasis. Results from head-to-head clinical trials that compared direct oral anticoagulant with low-molecular-weight heparin are also summarised, along with new evidence for the treatment and prophylaxis of VTE in patients with cancer.

Filiaciones:
Farge, D:
 Univ Paris, Ctr Reference Rare Syst Autoimmune Dis FAI2R, Internal Med UF04, Autoimmune & Vasc Dis Unit, Paris, France

 McGill Univ, Dept Med, Montreal, PQ H4A 3J1, Canada

Frere, C:
 Sorbonne Univ, Pitie Salpetriere Hosp, AP HP, Dept Haematol,UMRS 1166, Paris, France

Connors, JM:
 Harvard Med Sch, Brigham & Womens Hosp, Hematol Div, Boston, MA 02115 USA

Ay, C:
 Med Univ Vienna, Dept Med 1, Clin Div Hematol & Hemostaseol, Vienna, Austria

Khorana, AA:
 Cleveland Clin, Taussig Canc Inst, Cleveland, OH 44106 USA

 Cleveland Clin, Case Comprehens Canc Ctr, Cleveland, OH 44106 USA

Muno, ZA:
 Univ Complutense, Hosp Gen Univ Gregorio Maranon, Med Oncol Dept, Madrid, Spain

Brenner, B:
 Rambam Hlth Care Campus, Dept Hematol & Bone Marrow Transplantat, Haifa, Israel

Kakkar, A:
 Thrombosis Res Inst, London, England

 UCL, London, England

Rafii, H:
 Univ Paris, St Louis Hosp, AP HP, Eurocord, Paris, France

Solymoss, S:
 McGill Univ, Dept Med, Montreal, PQ H4A 3J1, Canada

Brilhante, D:
 Lisbon Ctr, Francisco Gentil Portuguese Inst Oncol, Lisbon, Portugal

:
 Univ Catolica Murcia, Hosp Germans Trias & Pujol, Dept Internal Med, Barcelona, Spain

Bounameaux, H:
 Univ Hosp Geneva, Fac Med, Div Angiol & Hemostasis, Geneva, Switzerland

Pabinger, I:
 Med Univ Vienna, Dept Med 1, Clin Div Hematol & Hemostaseol, Vienna, Austria

Douketis, J:
 McMaster Univ, Dept Med, Hamilton, ON, Canada
ISSN: 14702045





LANCET ONCOLOGY
Editorial
The Lancet Publishing Group, STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA, Reino Unido
Tipo de documento: Review
Volumen: 20 Número: 10
Páginas: 566-581
WOS Id: 000488267700020
ID de PubMed: 31492632
imagen Green Published

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