Sexually transmitted infections in young people and factors associated with HIV coinfection: an observational study in a large city
Por:
Sentis, A, Martin-Sanchez, M, Arando, M, Vall, M, Barbera, MJ, Ocana, I, Alsina, M, Martin-Ezquerra, G, Knobel, H, Gurgui, M, Vives, A, Coll, J, Cayla, JA, de Olalla, PG, Rius, C, Gil, S, Gorrindo, P, Clos, R, Sanchez, R, Ros, M, Masdeu, E, Simon, P, Santoma, MJ, Armengol, P, Curran, A, Ribera, E, Falco, V, Mateo, MG, Gutierrez, MM, Domingo, P, Lopez-Contreras, J, Villar, J, Guelar, A, Mothe, B, Fuertes, I, Cordon, AG, Blanco, JL, Garcia, F, Mallolas, J and Miro, JM
Publicada:
1 may 2019
Ahead of Print:
5 may 2019
Categoría:
Medicine (miscellaneous)
Resumen:
Objectives Young people are a critical target group for sexually transmitted infections (STI) surveillance due to their particular behavioural and social related vulnerability. The aim of this study was to describe the epidemiological characteristics and trends in the incidence of gonorrhoea, syphilis, HIV and venereal lymphogranuloma (LGV) among 15-24-year-olds in Barcelona, and to determine factors associated with HIV coinfection.
Design We performed a population-based incidence study covering the 2007-2015 period.
Participants All new cases of STI-HIV, gonorrhoea, infectious syphilis and LGV-notified to the epidemiological surveillance system in Barcelona between 2007 and 2015. 1218 cases were studied: 84.6% were men, 19.3% were 15-19 years old and 50.6% were born in Spain. Among men, 73.7% were men who have sex with men (MSM); among women, 85.6% were women that have sex with men.
Primary and secondary outcomes Incidence of HIV, gonorrhoea, infectious syphilis and LGV. HIV coinfection.
Results There was an increase in the incidence of gonorrhoea, from 1.9 cases per 10 000 people in 2007 to 7.6/10 000 in 2015 (p<0.01), in MSM from 27.1 to 228.8/10 000 (p<0.01). The incidence of syphilis increased from 0.4/10 000 in 2007 to 3.1/10 000 in 2015 (significant in men only, p<0.01), in MSM from 18.1 to 116.9/10 000 (p<0.01). The incidence of HIV showed a non-significant increase in men (p=0.27), and that of LGV remained stable (p=0.59). Factors associated with increased risk of HIV coinfection included being MSM (adjusted OR[ORa]=14.14, 95% CI 3.34 to 59.91) and having >10 sexual partners (ORa=4.11, 95% CI 1.53 to 11.01) or STI diagnosis during the previous 12 months (ORa=2.06; 95% CI 1.13 to 3.77).
Conclusions The incidence of gonorrhoea and syphilis among 15-24-year-olds increased, while HIV infection remained stable but with a high incidence among MSM. Being MSM, having sex with multiple partners and having a diagnosis of an STI in the previous 12 months were factors associated with HIV coinfection.
Filiaciones:
:
Publ Hlth Agcy Barcelona ASPB, Epidemiol Serv, Barcelona, Spain
Martin-Sanchez, M:
Publ Hlth Agcy Barcelona ASPB, Epidemiol Serv, Barcelona, Spain
Pompeu Fabra Univ, ASPB, Parc Salut Mar, Prevent Med & Publ Hlth Training Unit PSMar,UPF, Barcelona, Spain
Arando, M:
Univ Autonoma Barcelona, Hosp Vall dHebron, Barcelona, Spain
Vall, M:
Univ Autonoma Barcelona, Hosp Vall dHebron, Barcelona, Spain
Barbera, MJ:
Univ Autonoma Barcelona, Hosp Vall dHebron, Barcelona, Spain
Ocana, I:
Univ Autonoma Barcelona, Hosp Vall dHebron, Barcelona, Spain
Alsina, M:
Univ Barcelona, Hosp Clin Barcelona, Barcelona, Spain
Martin-Ezquerra, G:
Univ Autonoma Barcelona, Hosp del Mar, Barcelona, Spain
Knobel, H:
Univ Autonoma Barcelona, Hosp del Mar, Barcelona, Spain
Gurgui, M:
Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Barcelona, Spain
Vives, A:
Univ Autonoma Barcelona, Hosp Puigvert, Barcelona, Spain
Coll, J:
Univ Autonoma Barcelona, Hosp Tries & Pujol, Barcelona, Spain
Cayla, JA:
Publ Hlth Agcy Barcelona ASPB, Epidemiol Serv, Barcelona, Spain
CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain
Fdn TB Res Unit Barcelona, Barcelona, Spain
de Olalla, PG:
Publ Hlth Agcy Barcelona ASPB, Epidemiol Serv, Barcelona, Spain
CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain
Rius, C:
ASPB, Barcelona, Spain
Gil, S:
ASPB, Barcelona, Spain
Gorrindo, P:
ASPB, Barcelona, Spain
Clos, R:
ASPB, Barcelona, Spain
Sanchez, R:
ASPB, Barcelona, Spain
Ros, M:
ASPB, Barcelona, Spain
Masdeu, E:
ASPB, Barcelona, Spain
Simon, P:
ASPB, Barcelona, Spain
Santoma, MJ:
ASPB, Barcelona, Spain
Armengol, P:
Hosp Valle De Hebron, Barcelona, Spain
Curran, A:
Hosp Valle De Hebron, Barcelona, Spain
Ribera, E:
Hosp Valle De Hebron, Barcelona, Spain
Falco, V:
Hosp Valle De Hebron, Barcelona, Spain
Mateo, MG:
Hosp Santa Creu & Sant Pau, Barcelona, Spain
Gutierrez, MM:
Hosp Santa Creu & Sant Pau, Barcelona, Spain
Domingo, P:
Hosp Santa Creu & Sant Pau, Barcelona, Spain
Lopez-Contreras, J:
Hosp Santa Creu & Sant Pau, Barcelona, Spain
Villar, J:
Hosp del Mar, Barcelona, Spain
Guelar, A:
Hosp del Mar, Barcelona, Spain
:
Hosp Germans Tries & Pujol, Barcelona, Spain
Fuertes, I:
Hosp Clin Barcelona, Barcelona, Spain
Cordon, AG:
Univ Barcelona, Hosp Clin Barcelona, Barcelona, Spain
Hosp Clin Barcelona, Barcelona, Spain
Blanco, JL:
Hosp Clin Barcelona, Barcelona, Spain
Garcia, F:
Hosp Clin Barcelona, Barcelona, Spain
Mallolas, J:
Hosp Clin Barcelona, Barcelona, Spain
Miro, JM:
Hosp Clin Barcelona, Barcelona, Spain
Green Published, gold
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