Recommendations on the pathological report of pituitary tumors. A consensus of experts of the Spanish Society of Endocrinology and Nutrition and the Spanish Society of Pathology.
Por:
Picó A, Aranda-López I, Sesmilo G, Toldos-González Ó, Japón MA, Luque RM and Puig-Domingo M
Publicada:
12 jun 2021
Ahead of Print:
12 jun 2021
Resumen:
Pituitary neuroendocrine tumors (PitNETs) constitute, together with other tumors of the sellar region, 15-25% of intracranial neoplasms. In 2017, the World Health Organization proposed a new classification of PitNETs. The main innovation with respect to the 2004 classification was the recommendation to include in the immunohistochemical evaluation of PitNETs the determination of the transcription factors of the 3 pituitary cell lineages: Pit-1, Tpit and SF-1. Additionally, other clinicopathological classifications with a predictive capacity of tumor behavior during follow-up were proposed. Given these changes, it is appropriate to adapt the knowledge generated during the last 15 years to the daily practice of the treatment and monitoring of PitNETs at the Centers of Excellence in Pituitary Pathology. This document includes the positioning of the Spanish Society of Endocrinology and Nutrition (SEEN) and the Spanish Society of Pathology (SEAP) on the classification and denomination of the PitNETs and the information that the pathologist should provide to the clinician to facilitate the treatment and monitoring of these tumors.
Filiaciones:
Picó A:
Servicio de Endocrinología y Nutrición, Instituto de Investigación Sanitaria y Biomédica de Alicante-Hospital General Universitario de Alicante, Universidad Miguel Hernández, Alicante, Spain
Aranda-López I:
Servicio de Anatomía Patológica, Hospital General Universitario de Alicante/ISABIAL, Alicante, Spain
Sesmilo G:
Servicio de Endocrinología y Nutrición, Hospital Universitari Dexeus, Barcelona, Spain
Toldos-González Ó:
Sección de Neuropatología, Servicio de Anatomía Patológica, Hospital Universitario 12 de Octubre, Madrid, Spain
Japón MA:
Servicio de Anatomía Patológica, Hospital Universitario Virgen del Rocío, Sevilla, Spain
Luque RM:
Grupo Obesidad y Metabolismo, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Hospital Universitario Reina Sofía de Córdoba, Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
:
Servicio de Endocrinología y Nutrición, Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona (Barcelona), Spain
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