Activation of viral defense signaling in cancer
Por:
Gonzalez-Cao, M, Karachaliou, N, Santarpia, M, Viteri, S, Meyerhans, A and Rosell, R
Publicada:
29 ago 2018
Categoría:
Oncology
Resumen:
A coordinated action of innate and adaptive immune responses is required to efficiently combat a microbial infection. It has now become clear that cancer therapies also largely benefit when both arms of the immune response are engaged. In this review, we will briefly describe the current knowledge of innate immunity and how this can be utilized to prime tumors for a better response to immune checkpoint inhibitors. Comments on compounds in development and ongoing clinical trials will be provided.
Filiaciones:
Gonzalez-Cao, M:
Dexeus Univ Hosp, Quironsalud Grp, Rosell Oncol Inst IOR, C Sabino Arana 5, Barcelona 08028, Spain
Karachaliou, N:
Sagrat Cor Univ Hosp, Quironsalud Grp, Rosell Oncol Inst IOR, Barcelona, Spain
Santarpia, M:
Univ Messina, Dept Human Pathol G Barresi, Med Oncol Unit, Messina, Italy
Viteri, S:
Dexeus Univ Hosp, Quironsalud Grp, Rosell Oncol Inst IOR, C Sabino Arana 5, Barcelona 08028, Spain
Teknon Med Ctr, Quironsalud Grp, Rosell Oncol Inst IOR, Barcelona, Spain
Meyerhans, A:
Univ Pompeu Fabra, Dept Expt & Hlth Sci DCEXS, Infect Biol Lab, Barcelona, Spain
Inst Catalana Recerca & Estudis Avancats ICREA, Barcelona, Spain
:
Germans Trias & Pujol Univ Hosp, Catalan Inst Oncol, Badalona, Spain
Sagrat Cor Univ Hosp, Quironsalud Grp, Rosell Oncol Inst IOR, Barcelona, Spain
Dexeus Univ Hosp, Quironsalud Grp, Rosell Oncol Inst IOR, C Sabino Arana 5, Barcelona 08028, Spain
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