Time to reconcile research findings and clinical practice on upper limb neurorehabilitation


Por: Boccuni, L, Marinelli, L, Trompetto, C, Pascual-Leone, A and Munoz, JMT

Publicada: 19 jul 2022
Resumen:
The problemIn the field of upper limb neurorehabilitation, the translation from research findings to clinical practice remains troublesome. Patients are not receiving treatments based on the best available evidence. There are certainly multiple reasons to account for this issue, including the power of habit over innovation, subjective beliefs over objective results. We need to take a step forward, by looking at most important results from randomized controlled trials, and then identify key active ingredients that determined the success of interventions. On the other hand, we need to recognize those specific categories of patients having the greatest benefit from each intervention, and why. The aim is to reach the ability to design a neurorehabilitation program based on motor learning principles with established clinical efficacy and tailored for specific patient's needs. Proposed solutionsThe objective of the present manuscript is to facilitate the translation of research findings to clinical practice. Starting from a literature review of selected neurorehabilitation approaches, for each intervention the following elements were highlighted: definition of active ingredients; identification of underlying motor learning principles and neural mechanisms of recovery; inferences from research findings; and recommendations for clinical practice. Furthermore, we included a dedicated chapter on the importance of a comprehensive assessment (objective impairments and patient's perspective) to design personalized and effective neurorehabilitation interventions. ConclusionsIt's time to reconcile research findings with clinical practice. Evidence from literature is consistently showing that neurological patients improve upper limb function, when core strategies based on motor learning principles are applied. To this end, practical take-home messages in the concluding section are provided, focusing on the importance of graded task practice, high number of repetitions, interventions tailored to patient's goals and expectations, solutions to increase and distribute therapy beyond the formal patient-therapist session, and how to integrate different interventions to maximize upper limb motor outcomes. We hope that this manuscript will serve as starting point to fill the gap between theory and practice in upper limb neurorehabilitation, and as a practical tool to leverage the positive impact of clinicians on patients' recovery.

Filiaciones:
Boccuni, L:
 UAB, Inst Univ Neurorehabil, Inst Guttmann, Badalona, Spain

 Univ Autonoma Barcelona, Bellaterra, Spain

 Fundacio Inst Invest Ciencies Salut Germans Trias, Badalona, Spain

Marinelli, L:
 Univ Genoa, Dept Neurosci Rehabil Ophthalmol Genet Maternal &, Genoa, Italy

 IRCCS Osped Policlin San Martino, Dept Neurosci, Div Clin Neurophysiol, Genoa, Italy

Trompetto, C:
 Univ Genoa, Dept Neurosci Rehabil Ophthalmol Genet Maternal &, Genoa, Italy

 IRCCS Osped Policlin San Martino, Dept Neurosci, Div Neurorehabil, Genoa, Italy

Pascual-Leone, A:
 UAB, Inst Univ Neurorehabil, Inst Guttmann, Badalona, Spain

 Hebrew SeniorLife, Sidney Wolk Ctr Memory Hlth, Hinda & Arthur Marcus Inst Aging Res & Deanna, Boston, MA USA

 Hebrew SeniorLife, Deanna & Sidney Wolk Ctr Memory Hlth, Boston, MA USA

 Harvard Med Sch, Dept Neurol, Boston, MA USA

:
 UAB, Inst Univ Neurorehabil, Inst Guttmann, Badalona, Spain

 Univ Autonoma Barcelona, Bellaterra, Spain

 Fundacio Inst Invest Ciencies Salut Germans Trias, Badalona, Spain
ISSN: 16642295





Frontiers in Neurology
Editorial
Frontiers Media S.A., AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND, Suiza
Tipo de documento: Review
Volumen: 13 Número:
Páginas:
WOS Id: 000836367500001
ID de PubMed: 35928130
imagen Green Published, gold

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