Post COVID-19 Condition in Children and Adolescents: An Emerging Problem
Por:
Izquierdo-Pujol, J, Moron-Lopez, S, Dalmau, J, Gonzalez-Aumatell, A, Carreras-Abad, C, Mendez, M, Rodrigo, C and Martinez-Picado, J
Publicada:
11 may 2022
Resumen:
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection became a pandemic in 2020 and by March 2022 had caused more than 479 million infections and 6 million deaths worldwide. Several acute and long-term symptoms have been reported in infected adults, but it remains unclear whether children/adolescents also experience persistent sequelae. Hence, we conducted a review of symptoms and pathophysiology associated with post-coronavirus disease 2019 (post-COVID-19) condition in children and adolescents. We reviewed the scientific literature for reports on persistent COVID-19 symptoms after SARS-CoV-2 infection in both children/adolescents and adults from 1 January 2020 to 31 March 2022 (based on their originality and relevance to the broad scope of this review, 26 reports were included, 8 focused on adults and 18 on children/adolescents). Persistent sequelae of COVID-19 are less common in children/adolescents than in adults, possibly owing to a lower frequency of SARS-CoV-2 infection and to the lower impact of the infection itself in this age group. However, cumulative evidence has shown prolonged COVID-19 to be a clinical entity, with few pathophysiological associations at present. The most common post-COVID-19 symptoms in children/adolescents are fatigue, lack of concentration, and muscle pain. In addition, we found evidence of pathophysiology associated with fatigue and/or headache, persistent loss of smell and cough, and neurological and/or cardiovascular symptoms. This review highlights the importance of unraveling why SARS-CoV-2 infection may cause post-COVID-19 condition and how persistent symptoms might affect the physical, social, and psychological well-being of young people in the future.
Filiaciones:
Izquierdo-Pujol, J:
irsiCaixa AIDS Res Inst, Badalona, Spain
:
irsiCaixa AIDS Res Inst, Badalona, Spain
CIBER Enfermedades Infecciosas, Madrid, Spain
:
irsiCaixa AIDS Res Inst, Badalona, Spain
Gonzalez-Aumatell, A:
Autonomous Univ Barcelona, Germans Trias & Pujol Univ Hosp, Dept Pediat, Badalona, Spain
:
Autonomous Univ Barcelona, Germans Trias & Pujol Univ Hosp, Dept Pediat, Badalona, Spain
:
Autonomous Univ Barcelona, Germans Trias & Pujol Univ Hosp, Dept Pediat, Badalona, Spain
:
Autonomous Univ Barcelona, Germans Trias & Pujol Univ Hosp, Dept Pediat, Badalona, Spain
:
irsiCaixa AIDS Res Inst, Badalona, Spain
CIBER Enfermedades Infecciosas, Madrid, Spain
Univ Vic Cent Univ Catalonia UVic UCC, Dept Infect Dis & Immun, Vic, Spain
Catalan Inst Res, Adv Studies ICREA, Barcelona, Spain
gold, Green Published
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